Are you Clinically Depressed and feel exhausted all the time?
Iron is very important for sustaining good health.
Iron deficiencies can cause feeling exhausted, create
Clinical Depression, make us more susceptible to viruses,
cancer and a variety of degenerative conditions.
Likewise, iron excess or alteration in the iron-binding
capability resulting in free, unbound iron carries the
potential for causing or aggravating all diseases,
infections, cancers and toxicities.
Therefore is it necessary that we do not only strive to
both acquire adequate amounts of iron and rid ourselves of
excess iron, and that every effort is made to bind and
properly escort iron from the moment it enters the body
until it exits.
In addition, binding and escorting iron is particular
important during the detoxification process. Otherwise, the
many benefits iron provides are easily overshadowed by its
toxicity.
Discussing Body Iron is difficult and no single indicator
or combination of indicators is ideal for the assessment of
iron status in all clinical circumstances.
Each indicator may be affected by a variety of conditions
including infection, inflammation,liver disease and
malignancy, and these factors must be considered in
interpreting laboratory investigations.
Iron is essential to life, because of its unique ability to
serve as both an electron donor and acceptor.
But iron can also be potentially toxic.
Iron's ability to donate and accept electrons means that if
iron is free within the cell, it can catalyze the
conversion of hydrogen peroxide into free radicals. And
free radicals can cause damage to a wide variety of
cellular structures, and ultimately kill the cell.
To prevent that kind of damage, all life forms that use
iron bind the iron atoms to proteins.
That allows the cells to use the benefits of iron, but also
limit its ability to do harm.
The Free Radicals can be identified in a comprehensive
biochemical screening report.
Six subclinical defects have been identified that are
common to every degenerative disease.
Free Radicals are extremely reactive chemical entities that
arise normally from metabolism, and also from toxic
exposure.
When your iron status is out of balance, then there will be
free iron produced and this free iron is very toxic. Free
Iron, indicates that iron is not bound to protein. It is a
heavy metal.
Many proteins are enzymes that catalyze biochemical
reactions, and are vital to metabolism.
One example of this is that enzymes produced by chronic
inflammation, combined with damaging free radicals and
alterations in the other subclinical markers assessed cause
a breakdown in connective tissues.
Connective tissues make up the body's "superstructure" and
"guy wires" that literally holds the body together.
The words protein, polypeptide, and peptide are a little
ambiguous and can overlap in meaning.
Protein is generally used to refer to the complete
biological molecule in a stable conformation, whereas
peptide is generally reserved for short amino acid
oligomers often lacking a stable 3-dimensional structure.
However, the boundary between the two is ill-defined and
usually lies near 20-30 residues.
Polypeptide can refer to any single linear chain of amino
acids, usually regardless of length, but often implies an
absence of a defined conformation
The iron withholding mechanism occurs naturally at the
onset of every healthy, acute inflammatory response.
Given full recognition to the natural defence mechanism of
iron withholding allows health professionals to be far more
effective when building immunity, treating people for
cancer, iron deficiency, inflammation, excessive tiredness,
memory decline or depression.
The risk in amplified when laboratory testing is
inadequate; typical of many insurance driven health plans.
Similarly, there is risk in supplementing iron where the
decision to supplement is based solely on a low serum iron
reading.
To give an example, when in the chemistry it shows up that
a person has low serum iron, an elevated to high
Transferrin Iron Binding Capacity and a low Transferrin
Saturation, this is an indicator that there is free iron.
It also indicates that there is a Copper Deficiency.
Cerruloplasmin is a specialized copper-rich protein that
enters the Ferritin molecule to free iron, so it can be
attached to transferrin.
This is a pretty good marker, when it gets elevated, of a
copper deficiency.
Remember that the Cerruloplasmin is the copper bound
protein or protein bound copper is the compound that pulls
the iron out of the ferritin cage, puts it out on to the
transferrin leash and attaches it
to the leash.
If the Cerruloplasmin are not there then of course you can
have a lot of transferrin in the serum without the iron
molecules being attached to the leash.
Each one of these transferrins has two hooks on them so you
can put two irons on each leash but if the copper is not
there, if you are deficient and can't make the
Cerruloplasmin, what happens Transferrin Iron Binding
Capacity rises because you don't have iron actually
attached to enough of the transferrins.
When there is free iron, this also indicates that the iron
is not bound to the protein. One of the consequences of the
depleted amino acids pool is that this has an impact on the
neurotransmitters.
Therefore it could be helpful to access the iron status as
discussed and the amino acid pool.
The diagnosis of Clinical Depression could be dealt with an
additional different protocol, which might lead to better
outcomes.
By identifying the markers for disturbed iron status and
assisting you in developing a comprehensive strategy for
achieving a healthy iron status your risk of all disease
and toxicity and infection are lessened.
In addition to accurately measuring iron levels, strategies
for restoring iron balance need to take into account many
factors.
1. Maintaining a healthy intestinal mucosa
2. Sustaining adequate protein levels
3. Sustaining and aerobic versus anaerobic metabolism
4. Achieving a state of alkalinity versus acid stress
5. Maintaining a healthy cytochrome P450 system to rid the
body of organic solvents and other toxins that may hinder
protein-iron binding
6. Establishing a diet rich in whole eggs and cultured
dairy for individuals with a tendency towards free iron,
iron overload.
7. Recommending a phlebotomy program for those confirmed
with iron overload.
Transferrin, lactoferrin, lactoglobin and ovotransferrin
are iron-binding proteins. Transferrin, the only commonly
measured iron-binding protein that is synthesized by the
body, is readily taken up by receptors of both healthy
cells and cancer cells. Lactoferrin and lactoglobin,
derived from dairy foods, plus ovotransferrin (conalbumin)
from eggs binds tightly to free iron
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http://www.apneasleep-snoringtreatments.com
http://www.a-holistic-healthcoach-approach.com
Information about Free Radical Therapy can be obtained in
website http://www.apneasleep-snoringtreatments.com
Helena Ederveen, Clinical Nutritionist, has worked with the
biochemistry analysis based upon the Free Radical Therapy
for 6 years. Life Style changes are required in order to
influence changes in the biochemistry
